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Took me a while to figure out what all the ESMFold2 rage was about. At first, the benchmarking data didn't look super remarkable to me but it turns there are many impressive aspects: - Fully open source, open weights + massive ESM Atlas (1.1B structures vs 0.2B for AF3).- SOTA performance despite no MSA use. MSA search and triangular attention were simply taken out of the base model.- Direct consequence, super low latency inference: 1024-residue protein structure prediction in 9 secs, still outp

x.comSylvain Gariel

Took me a while to figure out what all the ESMFold2 rage was about. At first, the benchmarking data didn't look super remarkable to me but it turns there are many impressive

Sylvain Gariel (@SylvainGariel). 12 likes. Took me a while to figure out what all the ESMFold2 rage was about. At first, the benchmarking data didn't look super remarkable to me but it turns there are many impressive aspects: - Fully open source, open weights + massive ESM Atlas (1.1B structures vs 0.2B for AF3).- SOTA performance despite no ...

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