While scientists have had an idea of the molecular tools that cells use to replicate DNA -- the enzymes that unzip the double-stranded DNA and create 'daughter' copies -- they did not have a clear ...
The faithful and complete replication of chromosomes is essential to maintain genetic stability and prevent the accumulation of cancer-promoting mutations. Replication forks are vulnerable to stalling ...
Replication fork reversal is a complex transaction that requires the coordinated unwinding and annealing of parental and newly synthesized strands at the replication fork. Replication fork reversal is ...