Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...

A new study led by Nicolás Bologna, a CSIC researcher at the Center for Research in Agricultural Genomics (CRAG), sheds light on the crucial role of the N-terminal extension (NTE) of AGO proteins, ...

The process of translation by ribosomes, which functions as a factory of protein synthesis, may be impeded by ‘ribosome arrest peptides’ (RAPs). However, underlying mechanisms remain elusive.

Cancer biology increasingly recognizes that cancer stem cells (CSCs) represent a critical subpopulation within tumors, marked by their self-renewal, ...

Researchers identify a mechanism regulating MEF2C stability in acute myeloid leukaemia and demonstrate a peptide strategy that suppresses disease progression.

Cancer immunotherapy has transformed the treatment landscape for multiple malignancies; however, its clinical efficacy remains limited in many tumors due to ...

More than two decades ago, a research team in the lab of David Hafler, a Yale researcher who at the time was at Harvard, discovered a type of T cell in humans that suppresses the immune system; they ...

Thanks to a first-of-its-kind platform, we are starting to understand how the molecular engine responsible for transcription in mammals controls its speed. A team of researchers from The Rockefeller ...

Mitochondrial deoxyribonucleic acid (mtDNA) is essential for cellular energy production and overall cell function. Abnormalities in mtDNA are linked to various diseases and are also implicated in ...

Recent studies reveal that changes in gene regulation, not just gene sequences, are crucial for the evolution of animal ...