DJ-1 is a protein with wide subcellular distribution and pleiotropic functions. The loss-of-function mutations of DJ-1 are associated with autosomal recessive early-onset Parkinson's disease yet the ...

Sarco/endoplasmic reticulum–mitochondria communication and mitochondrial dynamics are essential regulators of mitochondrial function, cellular metabolism, and calcium homeostasis Sarco/endoplasmic ...

Calcium (Ca 2+) drives many cellular functions, though the way it controls quality of proteins in the endoplasmic reticulum (ER), a cellular organelle that synthesizes and transports proteins, has not ...

The endoplasmic reticulum is the protein-making factory within cells consisting of tightly stacked sheets of membrane studded with the molecules that make proteins. Now, researchers have refined a new ...