The committee noted that the clinical evidence showed Magtrace and Sentimag to be as effective as the dual technique for detecting sentinel lymph nodes, including malignant nodes. Other clinically ...

In the trials that served to establish the SLNB procedure, the false-negative rate varied between 5.5% and 16.7%, and the lowest false-negative rates were from studies in which preoperative ...

Older women with a very early, non-invasive breast cancer known as ductal carcinoma in situ (DCIS) gain no long-term benefit from undergoing a sentinel lymph node biopsy to see if the cancer has ...

The sentinel lymph node (SLN) is the lymph node that represents the 'gate-keeper' of the lymphatic basin; it is the first node to receive lymphatic drainage from the site of the primary tumor. SLN ...

Trials evaluating the omission of completion axillary-lymph-node dissection in patients with clinically node-negative breast cancer and sentinel-lymph-node metastases have been compromised by limited ...

A total of 751 women clinically node negative post-NACT underwent LAS (excision of lymph node [LN] and fat below first intercostobrachial nerve). Of these women, 730 also underwent SNB by dual ...

IntroductionLymph node involvement significantly impacts the prognosis of patients with gynecologic cancers, such as vulvar and cervical cancers. Traditional extensive lymph node dissection is ...

NICE commissioned an external assessment centre (EAC) to review the evidence submitted by the company. This section summarises that review. Full details of all the evidence are in the project ...