Crystallization conditions of an intact monoclonal IgG4 (immunoglobulin G, subclass 4) antibody were established in vapor diffusion mode by sparse matrix screening and subsequent optimization. The ...

Researchers furthered our understanding of the crystallization process in confined spaces by visualizing the ordering of colloidal particles in a droplet. The team conducted real-time microscopic ...

Research groups supported by industry tackle the challenges of continuous crystallization and process analytical technology. Continuous processing is attracting attention in the manufacture of both ...

Structural biology and structural genomics projects routinely rely on recombinantly expressed proteins, but many proteins and complexes are difficult to obtain by this approach. We investigated native ...