This narrated animation illustrates the process of protein synthesis, starting with chromosomal DNA inside the cell's nucleus. A gene is transcribed into messenger RNA, which leaves the nucleus and ...

Aminoacyl-tRNA synthetases (aaRSs) are ubiquitous enzymes that provide the critical link between the genetic code and protein biosynthesis. By precisely catalysing the attachment of amino acids to ...

tRNAs have a distinct cloverleaf secondary structure and an L-shaped tertiary structure. The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically ...

The diagram illustrates the key stages of protein synthesis in a eukaryotic cell. It begins with transcription to produce pre-mRNA in the nucleus (1), followed by post-transcriptional modification (2) ...

With the principles of molecular biology very much in the zeitgeist these days, we thought it would be handy to provide some sort of visual aid to help our readers understand the complex molecular ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

The process of 'translation' in protein synthesis involves formation of a peptide bond between two amino acids that are attached to two distinct transfer RNAs (tRNAs). For long, scientists have been ...

Researchers at ETH Zurich recently explained the role of a molecular complex that orchestrates the production of proteins in our cells. They now show that this complex also controls the processing of ...

Proteins are among the most important molecular building blocks of life. They are chains of amino acids assembled in our cells by ribosomes, the molecular "protein factories" of our bodies. The ...

Complex protein interactions at synapses are essential for memory formation in our brains, but the mechanisms behind these processes remain poorly understood. Now, researchers from Japan have ...