Just as the skeleton and muscles move the human body and hold its shape, the cells of the body are stabilized and moved by a cellular skeleton. This cellular skeleton is a dynamic structure, ...

The cells that make up our bodies are constantly exposed to a wide variety of mechanical stresses. For example, the heart and lungs have to withstand lifelong expansion and contraction, our skin has ...

How intermediate filaments polymerize and assemble in vivo is largely unknown. Now, a study reveals that this assembly is regulated by sumoylation of the cytoplasmic intermediate filament protein B-1A ...

The dynamic processes that occur during the growth of actin, via polymerization, and the breakdown of actin both play significant roles in cellular mechanisms like migration and adhesion. Due to the ...

The symptoms of neurodegenerative diseases like Alzheimer’s, frontotemporal dementia, and chronic traumatic encephalopathy (CTE) are different, but they have one feature in common: the presence of ...

Living cells are constantly exposed to a wide variety of mechanical stresses: heart and lungs must withstand expansion and contraction; our skin must be resistant to tearing whilst retaining ...