In Mendelian inheritance patterns, you receive one version of a gene, called an allele, from each parent. These alleles can be dominant or recessive. Non-Mendelian genetics don’t completely follow ...

"Monogenic" diseases, triggered by mutations in just one gene, may actually be more complex than scientists thought.

Chronic kidney disease (CKD) is a public health challenge that affects more than 800 million people worldwide. 1 CKD can be caused by a variety of disease processes. Many causes are difficult to ...

Scientists have identified novel genetic interactions that may contribute to congenital heart disease (CHD), a common birth defect. Scientists at the Icahn School of Medicine at Mount Sinai and ...

Familial Alzheimer’s disease is a rare, inherited form of Alzheimer’s that usually develops earlier than other forms of the disease. It’s due to specific genetic variants that tend to run in families.

Scientists have identified how specific genetic changes function in cells to influence disease risk and other human health ...

A genetics‑guided drug, compound 6, targets CARD9 to subtly calm gut inflammation in Crohn’s disease, pointing to safer, longer‑lasting, precision treatments.