A novel spatial transcriptomics atlas developed by Northwestern Medicine scientists may improve the understanding of niche cellular interactions in the gastrointestinal tract that promote the ...

In this collection we highlight a wide range of spatial imaging and spatial omics approaches that enable the spatial visualization of molecular targets in biological tissue. The protocols span between ...

Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper functioning. Understanding these spatial arrangements is important when ...

Integrated mass spectrometry imaging and spatial transcriptomics reveal that amyloid-β plaques differ in composition and local tissue responses, offering insight into Alzheimer’s disease heterogeneity ...

Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...

Transcriptomics is the study of the transcriptome, which is the complete set of RNA transcripts produced by the genome at a specific time or under particular conditions. It involves the analysis of ...