October 7, 2010 — The largest clinical trial to date of out-of-hospital hypertonic resuscitation shows it does not improve outcomes after traumatic brain injury. The disappointing results call into ...

Patients with a severe traumatic brain injury (and not in shock because of blood loss) who received out-of-hospital administration of hypertonic fluids (a solution with increased concentration of ...

Intravenous administration of isotonic fluids is the standard emergency treatment in the US for patients with severe blood loss, but bioengineering researchers have reported improved resuscitation ...

There are several theoretical benefits associated with the use of hypertonic saline with regard to hemodynamics, immune modulation, and ICP reduction. TBI is a disruption of the normal function of the ...

Research carried out at The University of Manchester has found further evidence that a simple solution, which is already used in IV drips, is an effective treatment for reducing inflammation. The ...

Fluid resuscitation with colloid and crystalloid solutions is a ubiquitous intervention in acute medicine. The selection and use of resuscitation fluids is based on physiological principles, but ...

THE application of hypertonic solutions speeds the appearance of clinical signs of cellular dehydration in proportion to the impermeability of the cellular membrane. Intravenous infusion of hypertonic ...

Research carried out at The University of Manchester has found further evidence that a simple solution, which is already used in IV drips, is an effective treatment for reducing inflammation. The ...

Fluid replacement therapy (intravenous infusion of fluid) attempts to reverse the effects of hypovolaemia by increasing circulatory blood volume and blood pressure back towards normal, in order to ...