An example of the measured changes in coupling can be seen in Fig. 1c, which shows how temperature and pressure affect the coupling (and thus stability) of the neighbouring hydrogen bonds between ...

Textbooks currently define a hydrogen bond as a weak electrostatic interaction that forms between a lone pair of electrons on an electronegative atom and a hydrogen atom bonded to another strongly ...

Hydrogen-bonding pairing regulates protein-ligand affinity; helps improve drug design. Infections with bacterium Clostridium difficile have rapidly become a significant medical problem in hospitals ...