GLP-1s are building a reputation as "wonder drugs." First characterized for their ability to improve insulin release and ...

Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

Cells are defined by the genes they express. In human cells, there are thousands of different protein coding genes, and the expression of those genes is carefully orchestrated and controlled by a ...

This article explains how diet creates sustained epigenetic changes that affect long-term health, disease risk, aging, and ...

Researchers identify a gene expression program in the living human brain that tracks with real-time neurotransmission, bridging the gap between genetics and electrical brain activity.

An international team of researchers has taken an important step toward understanding how gene expression is controlled across the human genome. The research is published in the journal Nature. The ...

A newly discovered code within DNA -- coined 'spatial grammar' -- holds a key to understanding how gene activity is encoded in the human genome. This breakthrough finding revealed a long-postulated ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Since the publication of the Human Genome Project, researchers have expanded the field of genomics to probe deeper into the underpinnings of human biology and disease, including studies of the body’s ...

Livestock breeders could soon have more tools to improve the health and quality of their animals, thanks to a recent study ...

DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...