Intracellular signaling proteins emerge as a key target in drug development

In a recently published review, a research team led by MedUni Vienna has highlighted a promising new approach to drug ...
EurekAlert!

RGS16 regulated by let-7c-5p promotes glioma progression by activating PI3K-AKT pathway

RGS proteins, including RGS16, are known to negatively regulate G-protein signaling pathways, which are implicated in various cancer-related processes such as cell migration, invasion, proliferation, ...
Nanowerk

AI drug discovery model surpasses AlphaFold by predicting if drugs work

The GPCRact AI model goes beyond AlphaFold3 by predicting whether drugs functionally activate G-protein-coupled receptors through allosteric signaling. (Nanowerk News) A research team has developed an ...
News Medical

Study highlights the role of RGS16 in glioma progression

RGS proteins, including RGS16, are known to negatively regulate G-protein signaling pathways, which are implicated in various cancer-related processes such as cell migration, invasion, proliferation, ...
ascopubs.org

Intracellular Signal Transduction Pathway Proteins As Targets for Cancer Therapy

Extended Lymph Node Dissection for Gastric Cancer: Who May Benefit? Final Results of the Randomized Dutch Gastric Cancer Group Trial Circulating cytokines, hormones, and growth factors control all ...
EurekAlert!

Heterotrimeric G-protein subunits regulate plant architecture, pod development, seed size, and symbiotic nodulation in Medicago truncatula

Beijing Zhongke Journal Publising Co. Ltd. In summary, these phenotypic analysis revealed that MtGα1 and MtGβ1 play important roles in plant growth and development, whereas MtRGS1 contributes to these ...