Many cancers are caused by fusion oncoproteins, molecules that aberrantly form when a rearrangement of DNA results in parts of two different proteins being expressed as one. Several fusion ...

There has been a missing puzzle piece in phase separation and its role in cancer. Now, researchers at the University of North Carolina (UNC) at Chapel Hill and the UNC Lineberger Comprehensive Cancer ...

A study published in the journal Science reveals how jumping fragments of human DNA, a type of genetic parasite, destabilize the cancer genome. Unstable genomes are a fertile playground for cancer ...

The mechanism by which breast cancer is formed in the cells of mammalian epithelium has been discovered. Although roughly 20 mutations accumulate annually in each epithelial cell until menopause, the ...

A team of researchers at VCU Massey Comprehensive Cancer Center has identified a new pathway through which mutations in the tumor suppressor p53 gene—found very frequently in human tumors—hijack DNA ...

Researchers have discovered the key role of the extracellular environment in dictating the ability of mutated cells to induce cancer formation. To form a cancer, cells need to accumulate oncogenic ...

Blood clots form in response to signals from the lungs of cancer patients—not from other organ sites, as previously thought—according to a preclinical study by Weill Cornell Medicine, Memorial Sloan ...

W.M. Keck Foundation grant will help scientists pioneer new technologies to find out Our microbiomes, the communities of microbes living in and on our bodies, influence everything from our weight to ...