Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the ...

Chemists want to trick cancer cells into taking up drug molecules by attaching the payloads to fatty acids. These cells grow rapidly compared to normal cells and they recognize fatty acids as ...

Metabolic Dysfunction-Associated Steatotic Liver Disease（MASLD） is characterized by excessive accumulation of lipids in hepatocytes and is closely associated with the rapid rise in insulin resistance, ...