Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using. Previously, this phenomenon was attributed to a decline ...

Named by the Evening Standard as one of the top 100 people shaping London in 2025, Professor David Nutt has authored over 500 research papers and more than 30 books. One of the world’s foremost ...

Drug addiction carries an extremely high risk of relapse, as cravings can be reignited by minor stimuli even long after one has stopped using ...

Ana Clara Bobadilla receives funding from the National Institute on Drug Abuse and the Brain & Behavior Research Foundation. Everyday human behavior is guided and shaped by the search for rewards.

Remarkable scientific progress over the past five decades has helped us develop knowledge of how drugs of abuse induce pleasure, reinforce use, and lead to the compulsive self-administration we call ...

People struggling with many addictions, ranging from opioids to gambling, are reporting similar experiences in clinics, on social media and around dinner tables.

GLP-1 drugs, originally developed for diabetes and obesity, may also curb addictive behaviors by acting on reward circuits in the brain. Early trials show reductions in alcohol intake, opioid seeking, ...