A gamma-globulin factor in the serum of patients with systemic lupus erythematosus that reacts with isolated cell nuclei 1 or nucleoprotein 2,3 has been detected in many ways. 4 The standard method of ...

Complement 3 glomerulopathy (C3G) is a rare kidney disorder—in many cases, the exact cause is unknown. Possible C3G causes include genetic mutations, autoantibodies, and certain autoimmune conditions.

C3G is caused by immune system dysfunction that can lead to kidney issues. When the kidneys don't work as they should, people can experience blood or protein in their urine, high blood pressure, and ...