A mechanism underlying neutrophil reprogramming in brain cancers has been uncovered, illuminating potential therapeutic targets to stop their pro-cancer effect. Tumor-infiltrating neutrophils are ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

The lab of Filippo Veglia, Ph.D., at The Wistar Institute has discovered a previously unknown mechanism for how aggressive brain cancers reprogram immune system cells from fighting cancer to enabling ...

Researchers have defined a new genetic disease caused by a mutation in the IVNS1ABP gene. The condition marks a rare ...

Life runs on information. In living systems, that information takes two main forms: the genome and the epigenome. The genome stays mostly stable. The epigenome, however, constantly shifts, shaped by ...

Employing a chemical reprogramming strategy to convert human epidermal keratinocytes into expandable sweat gland cells using six specific chemicals. Upon transplantation into damaged skin tissues in a ...

BLOOM (TAMPA) – Dr. Marissa McCarthy, Professor of Physical Medicine & Director of Brain Health and Strategic Partnerships, joins Gayle Guyardo, the host of Bloom, to share therapies that could help ...