The regulation of the cell cycle is a fundamental process ensuring the accurate replication and division of cells. Central to this regulation are the Cdc25 phosphatases, which activate ...

More than 200 metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found ...

Mechanisms associated with the genesis of cancer stem cell stemness, such as oxidative stress, tumor metastasis and recurrence, hypoxia induction, and tumor invasion. Genes & Diseases publishes ...

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it. Professor Néstor Oviedo, ...

Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and deadly forms of cancer, with a 5-year relative survival rate of only 13%. To understand cell fate decisions and progression in ...

Deep in our cells, a wide range of processes are occurring constantly. These cellular processes rely on enzymes to act as catalysts and set off a series of molecular interactions. There are still many ...

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

Researchers at the National University of Singapore (NUS) have identified a protein called tyrosine phosphatase 1B (PTP1B) as ...

Obesity significantly increases the risk of developing certain types of cancer through several interacting biological factors ...

Researchers profiled nearly 7 million individual cells from mice, identifying which cells are most vulnerable to aging and ...

Researchers at Scripps Research have identified a hidden filamentous architecture inside cellular droplets called biomolecular condensates, a finding that could reshape how scientists design drugs ...