A group of natural compounds attracting attention for their anti-aging potential has a dark side. New research shows how a ...

Preclinical research across multiple cancer types now shows that the NAD+ salvage pathway, the same biological mechanism targeted by popular anti-aging supplements like nicotinamide mononucleotide ...

Limonoids, produced during metabolism, are found in high levels in seeds, fruits, and peels of citrus fruits like lemons, limes, and oranges.  Munroni | Cancer ...

Polyamines—natural molecules found in every living cell—have become stars in the longevity world for their ability to boost cellular cleanup and support healthy aging. But there’s a dark twist: high ...

The mechanism by which cancer cells survive by self-regulating their proliferation signals has been revealed. By leveraging this principle, researchers successfully eliminated cancer cells in a leukem ...

The regulation of intracellular calcium is pivotal in driving various cellular processes, including proliferation, apoptosis, migration and gene transcription. In cancer, aberrant calcium signalling ...

After more than a decade of research, scientists have discovered the natural mechanism behind a novel form of cell death ...

Breast cancer risk screening using biomarkers and oestrogen metabolism markers could help predict individual risk before starting HRT.

A receptor involved in normal physiological processes may also drive breast cancer growth when overexpressed.

Fred Hutch Cancer Center scientists have developed an experimental strategy to give genetically engineered CAR T cells help they'd normally find within lymph nodes — but on the go, within the tumor.

Obesity significantly increases the risk of developing certain types of cancer through several interacting biological factors ...