The orchestration of T cell activation is central to immune defence and self-tolerance. Recent advances have revealed that T cells integrate signals from their antigen receptors alongside a network of ...

Dendritic cells (DCs) serve as pivotal sentinels of the immune system, bridging innate and adaptive responses by processing and presenting antigens to T cells. Their inherent versatility enables them ...

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

Chronic disease research increasingly points to the centrality of metabolic remodeling and mitochondrial dysfunction in dictating disease onset, severity, ...

In living cells, regulation of the electrochemical environment is supposed to be managed by ion channels—protein complexes that reside in cell membranes and assume definite shapes. So, it’s surprising ...

The same cellular renewal that keeps our bodies healthy might also fuel the growth of cancer. A UC Merced biologist has found that the brain could hold the key to stopping it. Professor Néstor Oviedo, ...

Critical proteins involved in animal stem cell regulation are much older than previously thought, predating the origin of animals that likely evolved more than 700 million years ago. This is the ...

More than 200 metabolic enzymes, many of which are normally tasked with producing energy in the mitochondria, are also found sitting directly on top of human DNA, according to a study published in ...

On Wednesday afternoon, Haifan Lin, the director of the Yale Stem Cell Center, discussed his innovative research findings in stem cell gene expression and regulation at Brown’s 2025 Mac V. Edds ...

By combining high-resolution genomic data with AI, researchers are uncovering the regulatory logic plants use to sense and survive environmental stress.

Stem cells in most organisms typically take cues from adjacent cells. But new research from the Stowers Institute for Medical Research has found that stem cells in the freshwater planarian Schmidtea ...