A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly ...

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have uncovered a critical mechanism that enables gastric cancer to spread to ...

A newly discovered gene switch may help turn chemotherapy-resistant pancreatic cancer into a treatable disease.

Researchers at the Cancer Research Institute and the Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, have ...

Scientists have identified a crucial molecular switch that decides whether pancreatic cancer cells resist chemotherapy or respond to it. The key player, a gene called GATA6, keeps tumours in a more ...

The regulation of intracellular calcium is pivotal in driving various cellular processes, including proliferation, apoptosis, migration and gene transcription. In cancer, aberrant calcium signalling ...

In a new study published in Science Signaling, University of Michigan researchers have shown that glucose levels sustain the increased STAT3 activation in colorectal cancer cells. Their findings ...

Cancer begins when mutations in specific genes override the body’s built-in controls on cell division, allowing rogue cells ...

A fluorescent probe for visualizing the signaling dynamics in metastatic cancer cells has been developed. A research team at the University of Turku (Finland), led by Johanna Ivaska and James Conway, ...

Innate immune sensors – known as pattern recognition receptors (PRRs) – detect specific molecular components of bacterial or ...