Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

Make no mistake, addiction is a neurological brain disorder. When the subject of addiction comes up, people often lean on familiar explanations. “They just need more willpower.” “Why can’t they stop ...

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

The roots of addiction risk may lie in how young brains function long before substance use begins, according to a new study from Weill Cornell Medicine. The investigators found that children with a ...

Researchers identify the anterior insula as the brain region responsible for biasing decisions toward alcohol over social rewards in addiction.

Addiction is one of the most intensely studied conditions in modern medicine, yet even with high‑resolution brain scans and genetic tools, scientists still cannot fully explain why some people get ...

Within the brain, chemical neurotransmitters like dopamine and norepinephrine regulate mood, emotions and many physiological and behavioral processes. Their imbalance can contribute to anxiety, ...

Cocaine addiction may affect how the body processes iron, leading to a build-up of the mineral in the brain, according to new research from the University of Cambridge. The study, published today in ...

Researchers at Virginia Tech are developing a new type of vaccine that could help prevent the harmful and addictive effects ...

New research suggests the weight-loss medications could be powerful tools in tackling substance use disorders.