Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...

Scientists at the University of Glasgow developed a bioengineered bone marrow (BM) model that helped them to evaluate potential use of a combined CRISPR-CAR T cell therapy in the treatment of acute ...

A cube of healthy bone is anything but solid. Inside it, countless tiny channels carry fluid and help cells move, feed, and ...

Researchers in Sweden have engineered a cell-free cartilage scaffold that can guide the body to rebuild damaged bone. By removing the cells but preserving the structure and natural growth signals, the ...

Bone implants often fail to fully integrate with surrounding tissue, limiting their effectiveness in regeneration. A natural but often overlooked cellular process could hold the key to better outcomes ...

Bone health relies on a balance between osteoblasts (builders) and osteoclasts (recyclers). Peak bone mass occurs in early adulthood; deficiencies during this window amplify fracture risks later in ...

Red blood cells carry oxygen from the lungs to every other organ, and blood-forming stem cells must make about 200 billion new red blood cells each day to keep the oxygen flowing. For many years, ...

Researchers found that mice lacking membrane ERα signaling in osteoblast lineage cells had significantly lower cortical bone mass, highlighting the pathway’s critical role in maintaining the strength ...