The origin of many diseases begins at the cellular level and involves multiple molecular interactions. However, previous methods have struggled to accurately observe changes in individual cells.
Advanced 3D cell models recreate the complexity of human tissues, enabling researchers to examine tumor progression, probe neurological disorders, and assess therapeutic candidates. By capturing the ...
Most cells in the human body exist in complex three-dimensional environments, yet they are still commonly studied on flat plastic dishes. These two-dimensional cultures distort cell behavior, limiting ...
Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...
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International collaboration produces detailed models of the 3D genome over time in cells
In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., at UMass Chan Medical School, has extensively mapped and analyzed the three ...
Advancing neurological disorder research requires model systems that more accurately reflect the human brain. 3D cell cultures, such as organoids and spheroids, have emerged as game-changers by better ...
3D cell cultures are no longer a futuristic idea. They’re already reshaping how we study diseases like cancer, offering more realistic models of how cells behave in the body. But despite their ...
Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...
Growing cells in three dimensions is critical for studying how tissues behave in the body, yet most laboratory platforms remain either too simple or too complex to use widely. Researchers now present ...
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